Pain out of proportion to physical examination is a hallmark finding in Hydrofluoric acid burns. Clinically, the morbidity of the burn is directly proportional to the concentration of HF, the duration of exposure, and the immediacy and adequacy of first aid measures (eg, copious irrigation). In the industrial setting, concentrations can reach levels >20%; however, the majority of patients are burned at 1% to 3% concentration, more commonly present in cleaning solutions and solvents. It is useful to categorize exposures based on the concentration of acid. Higher concentrations of acid results in more immediate pain and visible burn, followed by the development of grey areas, necrosis or ulceration, and possibly tenosynovitis and osteolysis, which can present as late manifestations. Lower concentrations (<20%) could result in delayed symptoms up to 24 h postexposure and, if left untreated, could progress through the same sequence as the high-concentration burns.

For all cutaneous Hydrofluoric acid burns, the clinician must include an assessment of any systemic effects. Late clinical manifestations of systemic toxicity include nausea, vomiting, abdominal pain, convulsions, hypotension, cardiac arrhythmias and cardiac failure. These findings are often not present in the majority of cases with low-concentration exposure. Patients are usually asymptomatic beyond the pain in the area of cutaneous exposure.

Hydrofluoric acid (HF) burn not only topical (skin and respiratory tract) serious injury, but also cause of fluorosis and hypocalcemia and death. Large doses of calcium is an important measure of treatment of HF burns, we are presented below. Clinical data: The group of six cases of HF in patients with burns, burns 0 .3% ~ 8% TBSA, in which five cases Ⅲ degree burns, superficial Ⅱ degree burns, they were then rinse with water 15min. Investigate 108 cases of hydrofluoric acid burn patients standardized methods. Methods: 108 cases of hydrofluoric acid burn patients early or thoroughly wash the wound site, to develop emergency procedures, first aid items ready, as soon as possible to help doctors treat calcium row, and do good calcium care, strengthen the observation. Timely detection of hypocalcemia and systemic symptoms, prevent heart and lung damage.